Napoli make a statement starting Noa Lang, Rasmus Hojlund and Scott McTominay, but not Kevin De Bruyne, while Como rely on Nico Paz, Martin Baturina and Tasos Douvikas.
It kicks off at the Stadio Diego Armando Maradona at 17.30 UK time (18.30 CEST).
COMO, ITALY – MAY 02: Maximo Perrone of Como 1907 competes for the ball with Alisson Santos of SSC Napoli during the Serie A match between Como 1907 and SSC Napoli at Giuseppe Sinigaglia Stadium on May 02, 2026 in Como, Italy. (Photo by Marco Luzzani/Getty Images)
The Partenopei opened their account with a 2-0 victory away to Genoa, although it took De Bruyne coming off the bench to break the deadlock there.
Coach Max Allegri was expected to stick with the same starting XI, which means the Belgian is again watching from the sidelines, as Andre Frank Zambo Anguissa takes the midfield reins.
However, there are two changes, as Matias Olivera is preferred to Leonardo Spinazzola, but above all Noa Lang goes from the transfer list to the starting XI instead of Alisson Santos.
Hojlund is supported by Lang, Matteo Politano and McTominay, with Alessandro Buongiorno and Luca Marianucci long-term absentees.
MILAN, ITALY – JANUARY 11: Scott McTominay of SSC Napoli celebrates scoring his team’s second goal with teammate Amir Rrahmani during the Serie A match between FC Internazionale and SSC Napoli at Giuseppe Meazza Stadium on January 11, 2026 in Milan, Italy. (Photo by Marco Luzzani/Getty Images)
Como started their season with a disappointing 1-1 draw at home to Udinese, so with their first ever Champions League campaign coming up, are beginning to feel the pressure of big club status.
Jayden Addai is still out of action, while Ignace van der Brempt was left behind pending a transfer to Sassuolo.
Summer signings Yan Couto, Trevoh Chalobah and Bruno Kaiki start in defence, with Luis Milla in midfield.
Nico Paz, Baturina and Assane Diao fan out behind Douvikas, with Mattia Liberali and new buy Samuele Ricci on the bench.
COMO, ITALY – MARCH 03: Como 1907 coach Cesc Fabregas issues instructions to his players Anastasios Douvikas and Martin Baturina during the Coppa Italia match between Como 1907 and FC Internazionale at Giuseppe Sinigaglia Stadium on March 03, 2026 in Como, Italy. (Photo by Marco Luzzani/Getty Images)
The last time Como came to the Stadio Maradona was in May, where they knocked Napoli out of the Coppa Italia quarter-final on penalties.
There was also some strong tension between Allegri and Cesc Fabregas when they crossed paths last season, trading insults and criticism both on the touchline and in the press room.
NAPLES, ITALY – JULY 14: New SSC Napoli head coach Massimiliano Allegri is unveiled at Teatro di San Carlo on July 14, 2026 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)
Napoli vs. Como line-upsNapoli: Meret; Di Lorenzo, Rrahmani, Rafa Marin, Olivera; Anguissa, Lobotka, McTominay, Politano, Hojlund, Lang
Como: Butez; Couto, Ramon, Chalobah, Valle; Milla, Da Cunha; Diao, Nico Paz, Baturina; Douvikas
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